Article
Composite synthetic lethal identification of membrane traffic inhibitors.
Proceedings of the National Academy of Sciences of the United States of America - 10 Apr 2007
Duncan Mara C, Ho David G, Huang Jing, Jung Michael E, Payne Gregory S
Abstract excerpt
Small molecule inhibitors provide powerful tools to characterize highly dynamic and complex eukaryotic cell pathways such as those mediating membrane traffic. However, a lack of easy and generalizable assays has constrained identification of novel inhibitors despite availability of diverse chemic...
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