Article
The -250G/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Mar 2008
Jiménez-Gómez Y, Pérez-Jiménez F, Marín C, Gómez P, Moreno R, Delgado J, Pérez-Martínez P, Gómez M J, López-Miranda J
Abstract excerpt
BACKGROUND AND AIM: The -250G/A promoter polymorphism of the hepatic lipase gene has been associated with changes in the activity of the enzyme. We investigated whether this polymorphism modifies the postprandial response of triacylglycerol-rich lipoproteins (TRL) in young normolipemic males. METHODS AND RESULTS: Fifty-one healthy apolipoprotein (apo) E3/E3 male volunteers (30 G/G and 21 carriers of the A allele)...
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