Article
The -250G-->A polymorphism in the human hepatic lipase gene promoter affects blood lipids in Chinese.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2006
Zhao Shuiping, Xie Xiangzhu, Nie Sai
Abstract excerpt
BACKGROUND: Human hepatic lipase (HL) is a glycoprotein that catalyzes the hydrolysis of triglycerides and phospholipids in all major classes of lipoproteins. We studied whether the hepatic lipase gene -250G(guanine)-->A(adenine) polymorphism affect blood lipids level and the coronary heart disease. METHODS: Two hundred and thirty subjects were included. Among them there were 122 patients with coronary heart...
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