Article
The influence of lipoprotein lipase gene variation on postprandial lipoprotein metabolism.
The Journal of clinical endocrinology and metabolism - 1 Sept 2004
López-Miranda José, Cruz Gracia, Gómez Purificación, Marín Carmen, Paz Elier, Pérez-Martínez Pablo, Fuentes Francisco J, Ordovas José M, Pérez-Jiménez Francisco
Abstract excerpt
Lipoprotein lipase (LPL) is one of the key enzymes in the metabolism of triacylglycerol-rich lipoproteins (TRL). We evaluated whether the association of LPL HindIII (H1/H2) and Serine447-Stop (S447X) polymorphisms may explain the interindividual variability observed during postprandial lipemia. Fifty-one healthy male volunteers (26 with the H2S447 genotype, 15 with the H1X447 genotype, and 10 with the H1S447...
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