Article
Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study.
Arzneimittel-Forschung - 1 Jan 2007
Uckun Fatih M, DuMez Darin, Qazi Sanjive, Tibbles Heather, Venkatachalam Taracad K
Abstract excerpt
The in vitro potency of GMP-grade stampidine (CAS 217178-62-6) was examined against 3 clinical HIV-1 isolates and 6 recombinant HIV-1 clones with multi-NRTI 'resistance (NRTI: nucleoside reverse transcriptase inhibitors). GMP-grade stampidine active drug substance (Lot #'s MPR-M0008.00-01 and MPR-M0008.01-01) as well as GMP-grade stampidine extracted from the clinical stampidine capsules (GMP-Grade Clinical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.