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Article

Effect of phlebotomy on hepcidin expression in hemojuvelin-mutant mice.

Blood cells, molecules & diseases - 1 Jan 2000

Krijt Jan, Niederkofler Vera, Salie Rishard, Sefc Ludĕk, Pelichovská Tereza, Vokurka Martin, Necas Emanuel

Abstract excerpt

Hemojuvelin (Hjv) is an essential component of the pathway regulating hepcidin (Hamp1) gene expression. Mice with targeted disruption of the Hjv gene (Hjv-/- mice) fail to upregulate hepatic Hamp1 expression following iron overload. The main aim of the study was to determine whether the Hjv protein is also necessary for Hamp1 downregulation. In addition, sex differences in Hamp1 expression in Hjv-/- mice were...

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Identifiers

PMID: 17395503
DOI: 10.1016/j.bcmd.2007.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of phlebotomy on hepcidin expression in hemojuvelin-mutant mice.PMID 17395503Read ↗

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