Article
Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice.
Journal of hepatology - 1 Jun 2004
Krijt Jan, Cmejla Radek, Sýkora Viktor, Vokurka Martin, Vyoral Daniel, Necas Emanuel
Abstract excerpt
BACKGROUND/AIMS: Male C57BL/6 and DBA/2 mice differ in their liver iron content. The aim of this study was to examine possible differences in the expression of hepcidin genes (Hamp and Hamp2) between the two strains. METHODS: Hepatic mRNAs were quantified by real-time PCR. RESULTS: Ferroportin1, transferrin receptor 2 and HAMP mRNA levels displayed no significant strain differences. However, HAMP2 mRNA levels...
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