Article
The association of serotonin transporter genetic polymorphisms and irritable bowel syndrome and its influence on tegaserod treatment in Chinese patients.
Digestive diseases and sciences - 1 Nov 2007
Li Yuyuan, Nie Yuqiang, Xie Jun, Tang Weizhan, Liang Peizhi, Sha Weihong, Yang Hui, Zhou Yonyjian
Abstract excerpt
The aims of this study were to investigate the relationship of genetic polymorphisms of the serotonin reuptake transporter and the clinical subtypes of irritable bowel syndrome and its influence on the efficacy of tegaserod in Chinese irritable bowel syndrome patients with constipation. Genetic polymorphisms were analyzed in 87 patients and 96 controls, then 41 irritable bowel syndrome patients with constipation...
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