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Article

Organization of H locus conserved repeats in Leishmania (Viannia) braziliensis correlates with lack of gene amplification and drug resistance.

Parasitology research - 1 Aug 2007

Dias Fabricio C, Ruiz Jeronimo C, Lopes Wilton C Z, Squina Fabio M, Renzi Adriana, Cruz Angela K, Tosi Luiz R O

Abstract excerpt

Resistance to antimonials is a major problem when treating visceral leishmaniasis in India and has already been described for New World parasites. Clinical response to meglumine antimoniate in patients infected with parasites of the Viannia sub-genus can be widely variable, suggesting the presence of mechanisms of drug resistance. In this work, we have compared L. major and L. braziliensis mutants selected in...

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PMID: 17393181
DOI: 10.1007/s00436-007-0528-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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