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Article

Defects in growth hormone receptor signaling.

Trends in endocrinology and metabolism: TEM - 1 Jan 2000

Rosenfeld Ron G, Belgorosky Alicia, Camacho-Hubner Cecelia, Savage M O, Wit J M, Hwa Vivian

Abstract excerpt

Severe growth failure and insulin-like growth factor (IGF) deficiency were first reported 40 years ago in patients who ultimately proved to have mutations in the gene encoding the growth hormone receptor (GHR). So far, over 250 similar patients, encompassing more than 60 different mutations of GH...

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Source

Identifiers

PMID: 17391978
DOI: 10.1016/j.tem.2007.03.004

Genes

GHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17391978-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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