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Article

Growth Hormone Insensitivity Associated with a <i>STAT5b</i> Mutation

17 Sept 2003

Abstract excerpt

This report documents that the syndrome of growth hormone insensitivity (severe short stature, increased secretion of growth hormone, but low serum concentrations of insulin-like growth factor I [IGF-I] and IGF–binding protein 3) in a teenage girl was due to a homozygous missense mutation in the gene for STAT5b, an essential component of the actions of growth hormone, as well as many other cytokine-induced functions.

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Share to Cytokine Signaling Pathways and Interactions
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Identifiers

PMID: 13679528
DOI: 10.1056/nejmoa022926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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