Article

Bleomycin induces fibrotic transformation of bone marrow stromal cells to treat height loss of intervertebral disc through the TGFβR1/Smad2/3 pathway

2020-11-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Lower back pain is often accredited to loss of intervertebral disc (IVD) height and compromised spine stability as a result of intervertebral disc degeneration (IVDD). We aim to locally use Bleomycin to induce the fibrotic transformation of bone marrow stromal cells (BMSCs) as a means to induce reparative fibrosis to slow down the height loss. <bold>Methods: </b...

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Literature Corpus work: 16e6b49d-0789-5ea8-9672-f8b28f2c9d43
DOI: 10.21203/rs.3.rs-71602/v2

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