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Article

Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch.

Proceedings of the National Academy of Sciences of the United States of America - 3 Apr 2007

Shih Hung Ping, Gross Michael K, Kioussi Chrissa

Abstract excerpt

Pitx2 expression is observed during all states of the myogenic progression in embryonic muscle anlagen and persists in adult muscle. Pitx2 mutant mice form all but a few muscle anlagen. Loss or degeneration in muscle anlagen could generally be attributed to the loss of a muscle attachment site in...

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Share to Branchial Region
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Share to Homeobox Protein PITX2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17384148
DOI: 10.1073/pnas.0701122104
PMCID: PMC1851590

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17384148-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch.PMID 17384148Read ↗

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