Article
The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Experimental and molecular pathology - 1 Jun 2007
Lakoski Susan G, Li Liwu, Langefeld Carl D, Liu Yongmei, Howard Timothy D, Brosnihan K Bridget, Xu Jianfeng, Bowden Donald W, Herrington David M
Abstract excerpt
UNLABELLED: Evidence suggests that interleukin-1 receptor-associated kinase-1 (IRAK1), fundamental in the toll-like receptor pathway (TLR), may play a more specific role in atherosclerosis. METHODS: Caucasian women (N=529) and men (N=467) from the Diabetes Heart Study (DHS) were genotyped at four loci within the IRAK1 gene located on the X chromosome. Generalized estimating equations (GEE1) were used to evaluate...
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