Heterogeneity of hepatitis C virus genotypes in hemophilia: relationship with chronic liver disease.

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Article

Heterogeneity of hepatitis C virus genotypes in hemophilia: relationship with chronic liver disease.

Blood - 1 Mar 1995

Preston F E, Jarvis L M, Makris M, Philp L, Underwood J C, Ludlam C A, Simmonds P

Abstract excerpt

In this study we have determined the hepatitis C virus (HCV) serotype and genotype in a cohort of 96 HCV-infected hemophiliacs and have examined the relationship between HCV genotype and severity of chronic liver disease as determined by liver biopsy. HCV serotype was determined by specific enzyme-linked immunosorbent assays (ELISAs) and genotype by restriction fragment length polymorphism (RFLP) and HCV viral...

Topics

Alanine Transaminase
Biopsy
Blood Coagulation Factors
Cohort Studies
Drug Contamination
England
Genetic Variation
Genome, Viral
Hemophilia A
Hepacivirus
Hepatitis C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver

Liver Cirrhosis

Polymorphism, Restriction Fragment Length

RNA, Viral

Serotyping

Severity of Illness Index

Virulence

Source

Open in PubMed

Identifiers

PMID: 7858256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7858256-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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