Article
Characterization of the interaction between anthrax toxin and its cellular receptors.
Cellular microbiology - 1 Apr 2007
Liu Shihui, Leung Howard J, Leppla Stephen H
Abstract excerpt
Mutations in capillary morphogenesis gene 2 (CMG2), one of the two closely related proteins that act as anthrax toxin receptors, cause two rare human autosomal recessive conditions, juvenile hyaline fibromatosis (JHF) and infantile systemic hyalinosis (ISH). Here we demonstrate that CMG2 proteins with certain JHF- and ISH-associated single amino acid substitutions in their von Willebrand factor A domain or...
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