Article
VCAM-1 ablation in nonhematopoietic cells in MxCre+ VCAM-1f/f mice is variable and dictates their phenotype.
Experimental hematology - 1 Apr 2007
Ulyanova Tatiana, Priestley Gregory V, Nakamoto Betty, Jiang Yi, Papayannopoulou Thalia
Abstract excerpt
OBJECTIVE: The goal of the present study was to assess the extent of vascular cell adhesion molecule-1 (VCAM-1) gene deletion in hematopoietic vs nonhematopoietic cells in the bone marrow (BM) of MxCre(+)VCAM-1(f/f) mice and its impact on the phenotypic features of these mice. METHODS: VCAM-1 ablation was evaluated at the genomic level by polymerase chain reaction (PCR), at the mRNA level by real-time PCR, and at...
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