Article
MHC class II alleles in Mexican patients with rheumatic heart disease.
International journal of cardiology - 1 Nov 2003
Hernández-Pacheco Guadalupe, Aguilar-García José, Flores-Domínguez Carmina, Rodríguez-Pérez José Manuel, Pérez-Hernández Nonanzit, Alvarez-Leon Edith, Reyes Pedro A, Vargas-Alarcón Gilberto
Abstract excerpt
BACKGROUND: Rheumatic heart disease (RHD) is an autoimmune sequel of group A streptococcal infection that has been associated with the presence of some major histocompatibility complex (MHC) genes. Thus, the aim of the present study was to investigate the role of class II alleles in the genetic susceptibility to RHD in Mexican patients and establish the relationship of these alleles with the pattern of valve...
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