Article
Corynebacterium diphtheriae employs specific minor pilins to target human pharyngeal epithelial cells.
Molecular microbiology - 1 Apr 2007
Mandlik Anjali, Swierczynski Arlene, Das Asis, Ton-That Hung
Abstract excerpt
Adherence to host tissues mediated by pili is pivotal in the establishment of infection by many bacterial pathogens. Corynebacterium diphtheriae assembles on its surface three distinct pilus structures. The function and the mechanism of how various pili mediate adherence, however, have remained poorly understood. Here we show that the SpaA-type pilus is sufficient for the specific adherence of corynebacteria to...
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