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Article

Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode.

Journal of bacteriology - 1 Aug 2013

Broadway Melissa M, Rogers Elizabeth A, Chang Chungyu, Huang I-Hsiu, Dwivedi Prabhat, Yildirim Suleyman, Schmitt Michael P, Das Asis, Ton-That Hung

Abstract excerpt

Toxigenic Corynebacterium diphtheriae strains cause diphtheria in humans. The toxigenic C. diphtheriae isolate NCTC13129 produces three distinct heterotrimeric pili that contain SpaA, SpaD, and SpaH, making up the shaft structure. The SpaA pili are known to mediate bacterial adherence to pharyngeal epithelial cells. However, to date little is known about the expression of different pili in various clinical...

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Identifiers

PMID: 23772071
DOI: 10.1128/JB.00500-13
PMCID: PMC3754579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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