Article
Calcium binding properties of the Kingella kingae PilC1 and PilC2 proteins have differential effects on type IV pilus-mediated adherence and twitching motility.
Journal of bacteriology - 1 Feb 2013
Porsch Eric A, Johnson Michael D L, Broadnax Angela D, Garrett Christopher K, Redinbo Matthew R, St Geme Joseph W
Abstract excerpt
Kingella kingae is an emerging bacterial pathogen that is being recognized increasingly as an important etiology of septic arthritis, osteomyelitis, and bacteremia, especially in young children. The pathogenesis of K. kingae disease begins with bacterial adherence to respiratory epithelium, which is dependent on type IV pili and is influenced by two PilC-like proteins called PilC1 and PilC2. Production of either...
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