Cancer stem cells – an old idea that’s new again: implications for the diagnosis and treatment of breast cancer

Abstract excerpt

The medical treatment of solid tumors is beset by two fundamental problems: the fact that even striking initial responses are often followed by drug-resistant recurrences, and the lack of predictive tools to design individualized treatment strategies. These therapeutic problems have a biological basis in the genetic heterogeneity and genomic instability of solid tumors. Traditionally, these were thought to result...

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