Article
Concurrent loss of heterozygosity and copy number analysis in adenoid cystic carcinoma by SNP genotyping arrays.
Laboratory investigation; a journal of technical methods and pathology - 1 May 2007
Yu Yongtao, Baras Alexander S, Shirasuna Kanemitsu, Frierson Henry F, Moskaluk Christopher A
Abstract excerpt
Adenoid cystic carcinoma (ACC) is one of the most common malignancies to arise in the salivary glands, yet very little is known of the genetic alterations that are involved in the pathogenesis of this disease. To further examine the genetic changes that underlie ACC, we analyzed genomic DNA obtained from 22 primary ACC and two ACC-derived cell lines by high-density oligonucleotide single-nucleotide polymorphism...
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