Article
The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis.
Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 2000
Lu J, Chang P, Richardson J A, Gan L, Weiler H, Olson E N
Abstract excerpt
Formation of numerous internal organs involves reciprocal epithelial-mesenchymal signaling and subsequent patterning and growth of the organ primordium. Capsulin is a basic helix-loop-helix transcription factor expressed in mesenchymal cells that encapsulate the epithelial primordia of internal organs, including the kidney and lung, as well as the epicardium, which gives rise to the coronary arteries. Capsulin is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.