Article
CUTL1 promotes tumor cell migration by decreasing proteasome-mediated Src degradation.
Oncogene - 30 Aug 2007
Aleksic T, Bechtel M, Krndija D, von Wichert G, Knobel B, Giehl K, Gress T M, Michl P
Abstract excerpt
Recently, we identified the homeodomain transcription factor CUTL1 as important mediator of cell migration and tumor invasion downstream of transforming growth factor beta (TGFbeta). The molecular mechanisms and effectors mediating the pro-migratory and pro-invasive phenotype induced by CUTL1 hav...
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