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Clinical, Cellular, and Molecular Aspects of Cancer Invasion

1 Apr 2003

Abstract excerpt

Invasion causes cancer malignancy. We review recent data about cellular and molecular mechanisms of invasion, focusing on cross-talk between the invaders and the host. Cancer disturbs these cellular activities that maintain multicellular organisms, namely, growth, differentiation, apoptosis, and tissue integrity. Multiple alterations in the genome of cancer cells underlie tumor development. These genetic...

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PMID: 12663862
DOI: 10.1152/physrev.00024.2002

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