Article
Characterization of glycoinositolphosphoryl ceramide structure mutant strains of Cryptococcus neoformans.
Glycobiology - 1 Jun 2007
Gutierrez Ana L S, Farage Layla, Melo Manuel N, Mohana-Borges Ronaldo S, Guerardel Yann, Coddeville Bernadete, Wieruszeski Jean-Michel, Mendonça-Previato Lucia, Previato Jose O
Abstract excerpt
In fungi, glycoinositolphosphoryl ceramide (GIPC) biosynthetic pathway produces essential molecules for growth, viability, and virulence. In previous studies, we demonstrated that the opportunistic fungus Cryptococcus neoformans synthesizes a complex family of xylose-(Xyl) branched GIPCs, all of which have not been previously reported in fungi. As an effort to understand the biosynthesis of these sphingolipids,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
