Evolutionary conservation of components of the protein translocation complex.

doi:10.1038/367654a0

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Article

Evolutionary conservation of components of the protein translocation complex.

Nature - 17 Feb 1994

Hartmann E, Sommer T, Prehn S, Görlich D, Jentsch S, Rapoport T A

Abstract excerpt

Protein translocation into the mammalian endoplasmic reticulum requires the Sec61p complex, which consists of three membrane proteins. The alpha-subunit, the homologue of Sec61p of yeast, shows some similarity to SecYp, a key component of the protein export apparatus of bacteria. In Escherichia c...

Topics

Amino Acid Sequence
Animals
Base Sequence
Biological Transport
Conserved Sequence
Dogs
Eukaryotic Cells
Humans
Membrane Proteins
Molecular Sequence Data
Mutation
Prokaryotic Cells
Proteins
SEC Translocation Channels
Sequence Homology, Amino Acid

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