Characterization of lethal alleles of D-elg, an ets proto-oncogene related gene with multiple functions in Drosophila development.

Article

Characterization of lethal alleles of D-elg, an ets proto-oncogene related gene with multiple functions in Drosophila development.

Oncogene - 1 Dec 1993

Schulz R A, Hogue D A, The S M

Abstract excerpt

We have used genetic complementation rescue to identify two lethal alleles of D-elg, an ets proto-oncogene related gene of Drosophila. Animals that are hemizygous or trans-heterozygous for the alleles die as pharate adults, demonstrating normal gene function is required to complete Drosophila dev...

Topics

Alleles
Animals
Drosophila
Embryonic and Fetal Development
Female
Genes, Insect
Genes, Lethal
Heterozygote
Mutation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ets
RNA Splicing
RNA, Messenger
Transcription Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.