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Article

Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila.

Current biology : CB - 3 Apr 2007

Chen Yu, Pane Attilio, Schüpbach Trudi

Abstract excerpt

Gametogenesis is a highly regulated process in all organisms. In Drosophila, a meiotic checkpoint which monitors double-stranded DNA breaks and involves Drosophila ATR and Chk2 coordinates the meiotic cell cycle with signaling events that establish the axis of the egg and embryo. Checkpoint activity regulates translation of the transforming growth-factor-alpha-like Gurken signaling molecule which induces dorsal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17363252
DOI: 10.1016/j.cub.2007.02.027
PMCID: PMC1905832

Genes

ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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