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Article

Drosophila rhino encodes a female-specific chromo-domain protein that affects chromosome structure and egg polarity.

Genetics - 1 Nov 2001

Volpe A M, Horowitz H, Grafer C M, Jackson S M, Berg C A

Abstract excerpt

Here we describe our analyses of Rhino, a novel member of the Heterochromatin Protein 1(HP1) subfamily of chromo box proteins. rhino (rhi) is expressed only in females and chiefly in the germline, thus providing a new tool to dissect the role of chromo-domain proteins in development. Mutations in rhi disrupt eggshell and embryonic patterning and arrest nurse cell nuclei during a stage-specific reorganization of...

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Identifiers

PMID: 11729157
DOI: 10.1093/genetics/159.3.1117
PMCID: PMC1461866

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