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Article

N6-methyladenine is an epigenetic marker of mammalian early life stress

18 Dec 2017

Abstract excerpt

Recent evidence described 6-methyladenine (6 mA) as a novel epigenetic regulator in a variety of multicellular species, including rodents; however, its capacity to influence gene expression in the mammalian brain remains unknown. We examined if 6 mA is present and regulated by early life stress associated with predator odor exposure (POE) within the developing rat amygdala. Our results provide evidence that 6 mA...

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PMID: 29273787
DOI: 10.1038/s41598-017-18414-7

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