Article
Models for loosely linked gene duplicates suggest lengthy persistence of both copies.
Journal of theoretical biology - 21 Jun 2007
O'Hely Martin, Wockner Leesa
Abstract excerpt
Consider the appearance of a duplicate copy of a gene at a locus linked loosely, if at all, to the locus at which the gene is usually found. If all copies of the gene are subject to non-functionalizing mutations, then two fates are possible: loss of functional copies at the duplicate locus (loss of duplicate expression), or loss of functional copies at the original locus (map change). This paper proposes a simple...
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