Models for loosely linked gene duplicates suggest lengthy persistence of both copies.

doi:10.1016/j.jtbi.2007.01.025

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Article

Models for loosely linked gene duplicates suggest lengthy persistence of both copies.

Journal of theoretical biology - 21 Jun 2007

O'Hely Martin, Wockner Leesa

Abstract excerpt

Consider the appearance of a duplicate copy of a gene at a locus linked loosely, if at all, to the locus at which the gene is usually found. If all copies of the gene are subject to non-functionalizing mutations, then two fates are possible: loss of functional copies at the duplicate locus (loss of duplicate expression), or loss of functional copies at the original locus (map change). This paper proposes a simple...

Topics

Chromosome Mapping
Gene Duplication
Gene Frequency
Genes, Duplicate
Humans
Mathematics
Models, Genetic
Mutation
Probability
Time Factors

Source

Open in PubMed

Identifiers

PMID: 17363002
DOI: 10.1016/j.jtbi.2007.01.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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