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Article

Developmental and adult phenotyping directly from mutant embryonic stem cells.

Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2007

George Sophia H L, Gertsenstein Marina, Vintersten Kristina, Korets-Smith Ella, Murphy John, Stevens Mary E, Haigh Jody J, Nagy Andras

Abstract excerpt

Tetraploid embryo complementation assay has shown that mouse ES cells alone are capable of supporting embryonic development and adult life of mice. Newly established F(1) hybrid ES cells allow the production of ES cell-derived animals at a high enough efficiency to directly make ES cell-based genetics feasible. Here we report the establishment and characterization of 12 new F(1) hybrid ES cell lines and the use...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17360545
DOI: 10.1073/pnas.0609277104
PMCID: PMC1838622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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