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Article

Beta cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2007

Strobel Oliver, Dor Yuval, Stirman Amy, Trainor Amanda, Fernández-del Castillo Carlos, Warshaw Andrew L, Thayer Sarah P

Abstract excerpt

Inflammatory injury to the pancreas results in regeneration of normal tissue and formation of metaplastic lesions of a ductal phenotype. These metaplastic ductal lesions (MDL) are called tubular complexes (TC), mucinous metaplasia, or pancreatic intraepithelial neoplasia. Because they are regularly found in chronic pancreatitis and pancreatic cancer, their formation is thought to represent a step in...

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Source

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Identifiers

PMID: 17360539
DOI: 10.1073/pnas.0605248104
PMCID: PMC1815470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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