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Article

Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways.

Developmental biology - 1 May 2007

Tyler David M, Baker Nicholas E

Abstract excerpt

Mutations in the expanded gene act as hyperplastic tumor suppressors, interfere with cell competition and elevate Dpp signaling. Unlike Dpp overexpression, ex causes few patterning defects. Our data suggest that patterning effects are partly masked by antagonistic roles of other signaling pathways that are also activated. ex causes proliferation of cells in the posterior eye disc that are normally postmitotic. ex...

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Identifiers

PMID: 17359963
DOI: 10.1016/j.ydbio.2007.02.004
PMCID: PMC2075468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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