Article
Escape of human immunodeficiency virus type 1 from broadly neutralizing antibodies is not associated with a reduction of viral replicative capacity in vitro.
Virology - 5 Jul 2007
Quakkelaar Esther D, Bunnik Evelien M, van Alphen Floris P J, Boeser-Nunnink Brigitte D M, van Nuenen Ad C, Schuitemaker Hanneke
Abstract excerpt
Although the majority of primary HIV-1 variants can be neutralized by broadly neutralizing antibodies such as b12, 2G12, 2F5 and 4E10, resistance to these antibodies has been reported as well. The ability of the broadly neutralizing antibodies to inhibit a variety of viruses suggests that their e...
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