Article
Human immunodeficiency virus type 1 superinfection occurs despite relatively robust neutralizing antibody responses.
Journal of virology - 1 Dec 2008
Blish Catherine A, Dogan Ozge C, Derby Nina R, Nguyen Minh-An, Chohan Bhavna, Richardson Barbra A, Overbaugh Julie
Abstract excerpt
Superinfection by a second human immunodeficiency virus type 1 (HIV-1) strain indicates that gaps in protective immunity occur during natural infection. To define the role of HIV-1-specific neutralizing antibodies (NAbs) in this setting, we examined NAb responses in 6 women who became superinfected between approximately 1 to 5 years following initial infection compared to 18 women with similar risk factors who...
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