Article
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies.
Nature medicine - 1 Jun 2005
Trkola Alexandra, Kuster Herbert, Rusert Peter, Joos Beda, Fischer Marek, Leemann Christine, Manrique Amapola, Huber Michael, Rehr Manuela, Oxenius Annette, Weber Rainer, Stiegler Gabriela, Vcelar Brigitta, Katinger Hermann, Aceto Leonardo, Günthard Huldrych F
Abstract excerpt
To determine the protective potential of the humoral immune response against HIV-1 in vivo we evaluated the potency of three neutralizing antibodies (2G12, 2F5 and 4E10) in suppressing viral rebound in six acutely and eight chronically HIV-1-infected individuals undergoing interruption of antiretroviral treatment (ART). Only two of eight chronically infected individuals showed evidence of a delay in viral rebound...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
