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Article

DNA adducts in granulocytes of hospital workers exposed to ethylene oxide.

American journal of industrial medicine - 1 Apr 2007

Yong Lee C, Schulte Paul A, Kao Chi-Yu, Giese Roger W, Boeniger Mark F, Strauss Gary H S, Petersen Martin R, Wiencke John K

Abstract excerpt

BACKGROUND: Ethylene oxide (EtO), an important industrial chemical intermediate and sterilant, is classified as a human carcinogen. Occupational EtO exposure in many countries is regulated at 1 ppm (8-hr TWA), but levels of EtO-DNA adducts in humans with low occupational EtO exposures have not been reported. METHODS: We examined the formation of N7-(2'-hydroxyethyl)guanine (N7-HEG), a major DNA adduct of EtO, in...

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PMID: 17354254
DOI: 10.1002/ajim.20443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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