Article
C-Reactive protein-induced endothelial microparticle generation in HUVECs is related to BH4-dependent NO formation.
Journal of vascular research - 1 Jan 2007
Wang Jie-Mei, Wang Yan, Huang Jun-Yi, Yang Zhen, Chen Long, Wang Li-Chun, Tang An-Li, Lou Zhou-Fen, Tao Jun
Abstract excerpt
BACKGROUND: C-reactive protein (CRP) has been proven to facilitate endothelial injury via reduced NO production. Endothelial microparticles (EMPs) have emerged as a novel marker of endothelial injury. METHODS: In vitro cultured human umbilical vein endothelial cells (HUVECs) were incubated with C...
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