Article
Increased circulating CD31+/CD42b-EMPs in Perthes disease and inhibit HUVECs angiogenesis via endothelial dysfunction.
Life sciences - 15 Jan 2021
Li Boxiang, Huang Qian, Lin Chengsen, Lu Rongbin, Wang Tiantian, Chen Xianxiang, Liu Zhengtang, Liu Yun, Wu Jianping, Wu Yang, Liao Shijie, Ding Xiaofei
Abstract excerpt
AIMS: Endothelial microparticles (EMPs) are extracellular vesicles secreted by endothelial cells. The purpose of this research is to explore that the clinical significance and roles in angiogenesis and endothelial dysfunction of circulating microparticles in Perthes disease. MAIN METHODS: We collected platelet-poor plasma (PPP) from patients and controls, then microparticles (MPs) were extracted. Flow cytometry...
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