Article
Domains in the XPA protein important in its role as a processivity factor.
Biochemical and biophysical research communications - 27 Apr 2007
Bartels Claudine L, Lambert Muriel W
Abstract excerpt
XPA is a protein essential for nucleotide excision repair (NER) where it is thought to function in damage recognition/verification. We have proposed an additional role, that of a processivity factor, conferring a processive mechanism of action on XPF and XPG, the endonucleases, involved in NER. The present study was undertaken to examine the domain(s) in the XPA gene that are important for the ability of the XPA...
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