Article
The DNA damage-recognition problem in human and other eukaryotic cells: the XPA damage binding protein.
The Biochemical journal - 15 Nov 1997
Cleaver J E, States J C
Abstract excerpt
The capacity of human and other eukaryotic cells to recognize a disparate variety of damaged sites in DNA, and selectively excise and repair them, resides in a deceptively small simple protein, a 38-42 kDa zinc-finger binding protein, XPA (xeroderma pigmentosum group A), that has no inherent catalytic properties. One key to its damage-recognition ability resides in a DNA-binding domain which combines a zinc...
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