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Retrospective analysis of coagulation factor II receptor (F2R) sequence variation and coronary heart disease in hypertensive patients.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2007

Gigante Bruna, Bellis Alessandro, Visconti Roberta, Marino Marina, Morisco Carmine, Trimarco Valentina, Galasso Gennaro, Piscione Federico, De Luca Nicola, Prince Jonathan A, de Faire Ulf, Trimarco Bruno

Abstract excerpt

OBJECTIVES: The purpose of this study was to evaluate the role of genetic variants within the coagulation factor II receptor (F2R) in the occurrence of coronary heart disease (CHD). METHODS AND RESULTS: Four SNPs (-1738 G/A, 2860 G/A, 2930 T/C, and 9113 C/A) and an ins/del polymorphism -506-/GGCCGCGGGAAGC (D/I), replicating a consensus sequence for Ets-1 transcription factor, and their related haplotypes were...

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PMID: 17347481
DOI: 10.1161/ATVBAHA.107.140541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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