Article
Interaction of genetic and environmental factors in a Drosophila parkinsonism model.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Mar 2007
Chaudhuri Anathbandhu, Bowling Kevin, Funderburk Christopher, Lawal Hakeem, Inamdar Arati, Wang Zhe, O'Donnell Janis M
Abstract excerpt
Catastrophic loss of dopaminergic neurons is a hallmark of Parkinson's disease. Despite the recent identification of genes associated with familial parkinsonism, the etiology of most Parkinson's disease cases is not understood. Environmental toxins, such as the herbicide paraquat, appear to be risk factors, and it has been proposed that susceptibility is influenced by genetic background. The genetic model...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
