Article
Fitness declines in Tobacco etch virus upon serial bottleneck transfers.
Journal of virology - 1 May 2007
de la Iglesia Francisca, Elena Santiago F
Abstract excerpt
It has been well established that populations of RNA viruses transmitted throughout serial bottlenecks suffer from significant fitness declines as a consequence of the accumulation of deleterious mutations by the onset of Muller's ratchet. Bottlenecks are unavoidably linked to different steps of the infectious cycle of most plant RNA viruses, such as vector-mediated transmissions and systemic colonization of new...
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