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Article

The nuclear import of the human T lymphotropic virus type I (HTLV-1) tax protein is carrier- and energy-independent.

The Journal of biological chemistry - 4 May 2007

Tsuji Takahiro, Sheehy Noreen, Gautier Virginie W, Hayakawa Hitoshi, Sawa Hirofumi, Hall William W

Abstract excerpt

HTLV-1 is the etiologic agent of the adult T cell leukemialymphoma (ATLL). The viral regulatory protein Tax plays a central role in leukemogenesis as a transcriptional transactivator of both viral and cellular gene expression, and this requires Tax activity in both the cytoplasm and the nucleus. In the present study, we have investigated the mechanisms involved in the nuclear localization of Tax. Employing a GFP...

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Identifiers

PMID: 17344183
DOI: 10.1074/jbc.M611629200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The nuclear import of the human T lymphotropic virus type I (HTLV-1) tax protein is carrier- and energy-independent.PMID 17344183Read ↗

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