Article
The nuclear import of the human T lymphotropic virus type I (HTLV-1) tax protein is carrier- and energy-independent.
The Journal of biological chemistry - 4 May 2007
Tsuji Takahiro, Sheehy Noreen, Gautier Virginie W, Hayakawa Hitoshi, Sawa Hirofumi, Hall William W
Abstract excerpt
HTLV-1 is the etiologic agent of the adult T cell leukemialymphoma (ATLL). The viral regulatory protein Tax plays a central role in leukemogenesis as a transcriptional transactivator of both viral and cellular gene expression, and this requires Tax activity in both the cytoplasm and the nucleus....
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