Additional support for linkage of schizophrenia and bipolar disorder to chromosome 3q29.

doi:10.1016/j.euroneuro.2007.01.004

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Article

Additional support for linkage of schizophrenia and bipolar disorder to chromosome 3q29.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jan 2000

Schosser Alexandra, Fuchs Karoline, Scharl Theresa, Leisch Friedrich, Bailer Ursula, Kasper Siegfried, Sieghart Werner, Hornik Kurt, Aschauer Harald N

Abstract excerpt

After publishing a genome scan and follow-up fine mapping, suggesting schizophrenia and bipolar disorder linkage to chromosome 3q29, we now genotyped 11 additional SNPs (single nucleotide polymorphisms), in order to narrow down a potential candidate region. Linkage was performed using the GENEHUNTER program version 2.1r3. A NPL score Z(all) of 3.891 (p=0.000156) was observed with SNP rs225. In short, we found...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 3
DNA Primers
Genetic Markers
Genotype
Humans
Polymorphism, Single Nucleotide
Reproducibility of Results
Schizophrenia
Telomere

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Open in PubMed

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PMID: 17344034
DOI: 10.1016/j.euroneuro.2007.01.004

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