Article
Initiation of actinorhodin export in Streptomyces coelicolor.
Molecular microbiology - 1 Feb 2007
Tahlan Kapil, Ahn Sang Kyun, Sing Anson, Bodnaruk Tetyana D, Willems Andrew R, Davidson Alan R, Nodwell Justin R
Abstract excerpt
Many microorganisms produce molecules having antibiotic activity and expel them into the environment, presumably enhancing their ability to compete with their neighbours. Given that these molecules are often toxic to the producer, mechanisms must exist to ensure that the assembly of the export apparatus accompanies or precedes biosynthesis. Streptomyces coelicolor produces the polyketide antibiotic actinorhodin...
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